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. 2012 Oct 15;109(44):17942–17947. doi: 10.1073/pnas.1208396109

Fig. 4.

Fig. 4.

Crystal structure of the β-catenin/aStAx-35 complex. (A) Cα superposition of the X-ray structures of β-catenin bound to the Axin-CBD (PDB ID 1QZ7) (18) and aStAx-35 (rmsd = 0.47 Å). (B) Fo-Fc difference map (grid) calculated using β-catenin alone from the Axin-liganded structure (PDB ID 1QZ7) (18) as a phasing model and the density for the final structure of the β-catenin/aStAx-35 complex. The Axin numbering system was retained throughout for the stapled peptides. (C and D) Two different views of the aStAx-35/β-catenin interaction, with selected interacting side-chains shown explicitly. Distances in angstroms to several nearby residues are shown (coordinates of the β-catenin/aStAx-35 complex structure have been deposited under PDB ID 4DJS).