TABLE 1.

Characteristics of participants according to quartiles of energy-adjusted total calcium intake per day in the Framingham Offspring Study, 1998–2001¹

	Energy-adjusted total calcium intake quartiles 2
	Women					Men
1 (n = 167)	2 (n = 167)	3 (n = 168)	4 (n = 167)	P-trend	1 (n = 133)	2 (n = 133)	3 (n = 133)	4 (n = 133)	P-trend
Median (IQR) (mg)	627 (141)	917 (190)	1305 (223)	1845 (412)	—	566 (103)	722 (69)	892 (106)	1339 (436)	—
Range (mg)	263–772	773–1127	1128–1557	1558–2821	—	8–652	653–803	804–1046	1047–3050	—
Age (y)	59	59	59	61	0.04	59	60	59	60	0.49
BMI (kg/m2)	29	28	27	26	<0.01	29	29	29	28	0.25
Current smoker (%)	14	7	10	9	0.23	11	11	6	9	0.38
Any alcohol consumption (%)	64	58	63	59	0.51	83	79	70	76	0.07
Type 2 diabetes (%)	10	7	7	7	0.34	5	13	11	13	0.09
Hypertension (%)	38	42	33	37	0.41	47	43	46	36	0.14
Coronary artery disease (%)	4	4	4	2	0.37	5	12	3	10	0.66
Cardiovascular disease (%)	5	11	6	7	0.95	8	18	5	11	0.75
SBP (mm Hg)	126	125	123	124	0.14	129	126	128	124	0.04
DBP (mm Hg)	74	73	73	72	0.07	78	76	76	74	0.01
Total cholesterol (mg/dL)	210	207	208	203	0.09	197	191	193	191	0.18
HDL cholesterol (mg/dL)	59	59	60	63	0.02	46	45	45	45	0.57
LDL cholesterol (mg/dL)	125	121	122	116	0.03	123	119	122	120	0.66
Triglyceride cholesterol (mg/dL)	132	136	127	118	0.04	151	147	132	130	0.03
Antihypertensives (%)	27	29	25	28	0.99	30	30	32	27	0.67
Lipid-lowering medications (%)	13	21	14	15	0.99	17	23	19	21	0.63
Statins (%)	13	20	14	13	0.73	17	21	17	23	0.47
Aspirin use (%)	23	25	29	24	0.64	31	35	39	47	<0.01
NSAIDs (%)	28	34	31	30	0.85	35	29	20	29	0.28
Osteoporosis medications (%)	5	4	8	19	<0.01	0	0	0	<1	0.06
Postmenopausal (%)	83	80	84	92	0.01	—	—	—	—	—
Estrogen use (%)	34	35	38	42	0.09	—	—	—	—	—

¹DBP, diastolic blood pressure; NSAIDs, nonsteroidal antiinflammatory drugs; SBP, systolic blood pressure.

²Quartiles are numbered from the lowest (quartile 1) to highest (quartile 4).