FIGURE 1.
Effects of dietary Se concentration on hepatic GPX1 activity (A), body weight (B), blood glucose concentration (C), and postmortem plasma insulin concentration (D) in WT and OE mice at 5 mo of age. Values are means ± SE, n = 3–4 (A and D) or n = 5–10 (B and C). Means for a given measure without a common letter differ, P < 0.05. GPX1, glutathione peroxidase-1; OE, GPX1 overexpressing; OE(+), Se-adequate GPX1 overexpressing mice; OE(−), Se-deficient GPX1 overexpressing mice; WT, wild-type; WT(+), Se-adequate wild-type mice; WT(−), Se-deficient wild-type mice.