TABLE 2.
Discrete time hazard models of keratotic skin lesion risk in relation to quartiles of nutrient intake (HEALS)1
| Quartiles of nutrient intake |
|||||||||
| Nutrient | Q4 (highest) |
Q3 |
Q2 |
Q1 (lowest) |
P-trend | ||||
| n | n | HR (95%CI) | n | HR (95%CI) | n | HR (95%CI) | |||
| Retinol equivalents, μg/d | 4439 | 1 | 4331 | 1.45 (0.59–3.54) | 4245 | 1.66 (0.69–4.01) | 4246 | 2.36 (1.06–5.27) | 0.53 |
| Calcium, mg/d | 4422 | 1 | 4265 | 1.54 (0.56–4.03) | 4221 | 2.10 (0.88–5.02) | 4353 | 2.56 (1.04–6.25) | 0.27 |
| Carbohydrate, g/d | 4369 | 1 | 4113 | 1.00 (0.43–2.26) | 4339 | 1.17 (0.58–2.37) | 4440 | 0.66 (0.21–1.50) | 0.45 |
| Cholesterol, mg/d | 4385 | 1 | 4387 | 2.41 (0.94–6.14) | 4356 | 1.87 (0.72–4.87) | 4133 | 1.36 (0.49–3.72) | 0.64 |
| Copper, mg/d | 3860 | 1 | 4285 | 0.77 (0.29–2.02) | 4504 | 1.26 (0.55–2.86) | 4612 | 1.87 (0.84–3.84) | 0.24 |
| Monounsaturated fats, g/d | 4432 | 1 | 4197 | 0.79 (0.34–1.82) | 4182 | 1.12 (0.49–2.56) | 4450 | 0.86 (0.41–1.79) | 0.66 |
| Polyunsaturated fats, g/d | 4051 | 1 | 4178 | 1.17 (0.47–2.91) | 4560 | 1.01 (0.44–2.31) | 4472 | 0.69 (0.29–1.65) | 0.36 |
| Saturated fats, g/d | 4424 | 1 | 4257 | 1.26 (0.54–2.89) | 4065 | 1.19 (0.47–3.01) | 4515 | 1.46 (0.67–3.21) | 0.31 |
| Fiber, g/d | 4302 | 1 | 4090 | 2.22 (0.91–5.06) | 4335 | 1.04 (0.36–3.01) | 4534 | 3.31 (1.44–7.60) | 0.07 |
| Folate, μg/d | 4387 | 1 | 4253 | 1.81 (0.75–4.35) | 4246 | 1.72 (0.68–4.31) | 4375 | 2.94 (1.26–6.8) | 0.16 |
| Iron, mg/d | 4320 | 1 | 4181 | 1.74 (0.69–4.40) | 4261 | 1.76 (0.68–4.53) | 4499 | 2.49 (1.03–6.00) | 0.3 |
| Magnesium, mg/d | 4412 | 1 | 4147 | 1.18 (0.49–2.8) | 4302 | 0.92 (0.38–2.20) | 4400 | 1.38 (0.63–3.02) | 0.95 |
| Manganese, mg/d | 4098 | 1 | 4277 | 0.68 (0.31–1.50) | 4418 | 0.65 (0.30–1.42) | 4468 | 0.57 (0.26–1.26) | 0.08 |
| Niacin, mg/d | 4017 | 1 | 4281 | 1.04 (0.50–2.19) | 4473 | 1.16 (0.57–2.38) | 4490 | 0.67 (0.27–1.65) | 0.29 |
| Potassium, mg/d | 4403 | 1 | 4279 | 0.89 (0.37–2.14) | 4249 | 1.39 (0.60–3.22) | 4330 | 1.92 (0.88–4.15) | 0.56 |
| Protein, g/d | 4369 | 1 | 4275 | 1.21 (0.51–2.82) | 4197 | 1.85 (0.83–4.10) | 4420 | 1.02 (0.44–2.36) | 0.89 |
| Riboflavin, mg/d | 4267 | 1 | 4262 | 1.09 (0.39–2.98) | 4306 | 1.87 (0.76–4.57) | 4426 | 2.55 (1.06–6.16) | 0.2 |
| Selenium, mg/d | 4364 | 1 | 4151 | 0.85 (0.37–1.95) | 4330 | 0.82 (0.36–1.84) | 4416 | 0.56 (0.26–1.23) | 0.23 |
| Sodium, mg/d | 4290 | 1 | 4323 | 1.35 (0.57–3.25) | 4264 | 1.49 (0.61–3.65) | 4384 | 1.72 (0.73–4.03) | 0.95 |
| Thiamin, mg/d | 3596 | 1 | 4451 | 1.54 (0.64–3.71) | 4637 | 1.22 (0.46–3.21) | 4577 | 2.56 (1.07–6.11) | 0.2 |
| Total lipid, g/d | 4427 | 1 | 4260 | 1.21 (0.54–2.71) | 4092 | 1.00 (0.39–12.6) | 4482 | 1.33 (0.62–2.84) | 0.4 |
| Vitamin A, IU/d | 4441 | 1 | 4307 | 1.81 (0.76–4.27) | 4265 | 1.64 (0.66–4.01) | 4248 | 2.56 (1.14–5.74) | 0.44 |
| Vitamin B-6, mg/d | 4063 | 1 | 4189 | 0.67 (0.27–1.63) | 4448 | 0.82 (0.35–1.93) | 4561 | 1.59 (0.76–3.32) | 0.42 |
| Vitamin B-12, mg/d | 4385 | 1 | 4415 | 1.19 (0.52–2.70) | 4345 | 1.46 (0.65–3.25) | 4116 | 0.94 (0.41–2.14) | 0.86 |
| Vitamin C, mg/d | 4420 | 1 | 4306 | 1.39 (0.62–3.09) | 4282 | 0.95 (0.39–2.28) | 4253 | 2.29 (1.08–4.86) | 0.03 |
| Vitamin E, mg/d | 4252 | 1 | 4105 | 1.54 (0.61–3.87) | 4388 | 1.32 (0.51–3.39) | 4516 | 2.75 (1.30–5.83) | 0.05 |
| Zinc, mg/d | 4218 | 1 | 3947 | 1.02 (0.45–2.26) | 4543 | 1.02 (0.45–2.29) | 4553 | 1.14 (0.54–2.40) | 0.22 |
1
HEALS, Health Effects of Arsenic Longitudinal Study.