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. 2012 Aug 27;33(22):2813–2820. doi: 10.1093/eurheartj/ehs259

Table 3.

Hospitalizations expressed per patient for all patients and for patients actually hospitalized during the trial

Ivabradine (n = 3241) Placebo (n = 3264) P-value
Hospitalizations for worsening heart failure (number of patients)
 No hospitalization 2727 (84%) 2592 (79%)
 1 hospitalization 325 (10%) 389 (12%)
 2 hospitalizations 99 (3%) 155 (5%)
 ≥3 hospitalizations 90 (3%) 128 (4%)
Hospitalizations for worsening heart failure (number of events)
 Total number of hospitalization events 902 1211 0.0002
 Number of events per patient
 Whole population 0.3 0.4
 Patients with ≥1 hospitalization 1.8 1.8
Hospitalizations for any cause (number of patients)
 No hospitalization 2010 (62%) 1908 (58%)
 1 hospitalization 613 (19%) 646 (20%)
 2 hospitalizations 297 (9%) 313 (10%)
 ≥3 hospitalizations 321 (10%) 397 (12%)
Hospitalizations for any cause (number of events)
 Total number of hospitalization events 2661 3110 0.001
 Number of events per patient
 Whole population 0.8 1.0
 Patients with ≥1 hospitalization 2.2 2.3

P-values comparing patients in the ivabradine and placebo groups (Poisson's regression model).