Table 3.

Complication Frequency

Complication Type	Full Dataset (n=368) Number (%)	Reduced Dataset (n=349) Number (%)
Any Complication	129 (35.1)	83 (23.8)
Muscle Weakness	80 (21.7)	51 (14.6)
Phlebitis	33 (9.0)	32 (9.2)
Gastrointestinal Upset	15 (4.1)	15 (4.3)
Respiratory Failure	14 (3.8)	0 (0)
Hyperkalemia	12 (3.3)	0 (0)
Excessive Secretions	3 (0.8)	3 (0.9)
Other Complications	30 (8.2)*	13 (3.7)**

^*Other complications for the full dataset included: pulmonary edema (N=6), difficulty mixing dantrolene or precipitate in the IV (N=5), pain on injection (N=3), swollen extremity (N=2), concomitant decrease in cardiac output (N=2), prolonged mechanical ventilation (N=2), and hypotension, decreased hearing for 24 hours, blurred vision, difficulty opening eyes, anxiety for several minutes after injection, dysphoria, disorientation, somnolence, generalized weakness, increased alanine aminotransferase (ALT) on the second postoperative day, hyponatremia, each noted once in the full dataset. Some subjects had more than one complication.

^**Other complications for the reduced dataset included: difficulty mixing dantrolene or precipitate in the IV (N=5), pain on injection (N=3) and swollen extremity, decreased hearing for 24 hours, blurred vision, dysphoria, disorientation, somnolence, each noted once in the reduced dataset. Some subjects had more than one complication.