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. 2012 Nov 14;7(11):e49463. doi: 10.1371/journal.pone.0049463

Table 3. The 10 most different fold changes miRNAs between peak and late lactation.

miRNAs Reads Nor_ Reads F_ change P_ Value Sig_ level
Peak lactation Late lactation Peak lactation Late lactation
miR-17a* 0 54,914 0.01 7,435 19.50 0 **
miR-5425 0 6,766 0.01 916 16.48 0 **
miR-4754 0 6,326 0.01 856 16.37 0 **
miR-3138 10,637 0 559 0.01 −15.77 0 **
miR-125a* 15,723 0 826 0.01 −16.33 0 **
miR-125* 20,053 0 1,052 0.01 −16.68 0 **
miR-29-3p 21,450 0 1,126 0.01 −16.78 0 **
miR-3966 25,136 0 1,320 0.01 −17.01 0 **
miR-3175 27,377 0 1,438 0.01 −17.13 0 **
miR-881 29,370 0 1,542 0.01 −17.23 0 **

Note: Nor_Reads: Normalized reads, the results of Solexa sequencing, Normalization formula: Normalized expression = Actual miRNA count/Total count of clean reads×1,000,000; F_change: Fold_changes (Log2 Late lactation/Peak lactation), fold changes of miRNAs in both samples, – represents down regulation in late lactation; P_Value: P values manifest the significance of miRNAs differential expression between two samples; Sig_level: Significance_level, # represents no significant difference, * represents significant difference;