Figure 8. Extract of AMK inhibits the fat accumulation in HFD-induced obesity mice.

Mice (n = 8 per group) were orally administrated with vehicle or extract of AMK (62.5 mg/kg/day) with HFD for 8 weeks. Normal control group was administrated normal diet (ND) fed with vehicle. Negative control group was administrated HFD with vehicle. Positive control group was administrated HFD with xenical (62.5 mg/kg/day). (A) Morphology of changed fat tissues. (B) Comparison of fat pad weight from abdominal subcutaneous and perrenal white adipose tissues. (C) Histological analysis of the adipose tissues. (C) Panel a: normal control, panel b: negative control, panel c: positive control and panel d: treatment of AMK extract. (D) Comparison of adipocyte cells size (average size, mm²). (E) H&E staining of kidney tissue. Sections were stained with hematoxylin and eosin dye, and using a light microscope. Each bar represents mean ± S.D. form fat tissues of eight mice. *P<0.05 vs. negative control and **P<0.01 vs. negative control.