Table 2. Characterization of mitoxantrone-loaded nanoparticles.
Sample | Drug/carrier (w/w)a | Diameter (nm)b | Encapsulation (%)c | Loading capacity (%)d |
CHP | 1/10 | 168.6±3.3 | 58.6±3.14 | 7.12±0.24 |
CHCP | 1/10 | 192.7±4.2 | 50.8±2.26 | 6.14±0.16 |
Mitoxantrone/CHP or CHCP NPs (mg/mg).
Size and size distribution (mean value ± S.D) determined by dynamic light scattering with three times.
Encapsulation efficiency (mean value ± S.D) determined by UV spectrophotometry at 608 nm with three times.
Loading capacity of NPs (mean value ± S.D) determined by UV spectrophotometry at 608 nm with three times.