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. 2012 Nov 14;7(11):e49237. doi: 10.1371/journal.pone.0049237

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© 2012 Li et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Quantitative real-time PCR from myocardium RNA extracts revealed that mRNA levels for (A) superoxide dismutase (SOD)-1, (B) glutathione peroxydase (GPx)-4, (C) cytochrome-c oxidase were significantly increased after 24 h and (D) matrix metalloproteinase (MMP)-9 following 6 h and 24 h compared with the control group. However, mRNA-levels of (E) L-Type calcium-channel (Ca_v1.2), (F) sarco(endo)plasmic Ca²⁺-ATPase (SERCA)-2 and (G) sodium-potassium Adenosine Triphosphatase (Na⁺/K⁺-ATPase) remained unchanged following ethanol administration compared to the control group. Eth indicates ethanol. *p<0.05 versus control,^#p<0.05 versus ethanol 1 h, ^$p<0.05 versus ethanol 6 h.