Figure 7. Effect of acute ethanol exposure on donor heart function 1 h or 24 h after transplantation.

One hour and 24 h after transplantation, in which donors received ethanol 6 h or 24 h prior to explantation, significantly lower (A, E) dP/dt_max (maximal slope of the systolic pressure increment) and (B, F) dP/dt_min (maximal slope of the diastolic pressure decrement) were observed when compared with the control-group. Although (C) LV systolic pressure (LVSP) and (D) LV developed pressure, as indexes of myocardial contractile function, were significantly decreased in the 24 h ethanol+1 h I/R group 1 h after transplantation. However, 24 h after transplantation, (G) LVSP and (H) LV developed pressure were significantly decreased in both 6 h ethanol+24 h I/R and 24 h ethanol+24 h I/R groups compared with the control-group. I/R indicates ischemia/reperfusion, LVV left-ventricular volume. *p<0.05 versus 1 h I/R group.