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. 2012 Nov 14;7(11):e49027. doi: 10.1371/journal.pone.0049027

Figure 1. Schematic representation of HvHMA1.

Figure 1

HvHMA1 contains the conserved P-type ATPase actuator (A), phosphorylation (P) and nucleotide binding (N) domains. HvHMA1 is here presented with 8 transmembrane segments according to alignment with AtHMA7. HvHMA1 contains an extended N-terminus with a predicted chloroplast target peptide (light gray box) and a long stretch of putative metal-binding histidine residues as indicated. It contains the conserved P-type ATPase phosphorylation sequence DKTGT as well as the P1B-ATPase putative metal binding-site SPC and the HEGG motif. Furthermore a putative Tg binding sequence DEFGEHYSK is presented in TM5.