Table 1. Cellular infiltration, vasculopathy and tissue fibrosis in heart and skin grafts.
Donor: bm12 | Heart transplant | Skin transplant | ||
Recipient: | B6 | Apn–/– | B6 | Apn–/– |
CD4 | 36±2 | 6±1*** | 20±2 | 0*** |
CD8 | 11±1 | 1±0*** | 30±2 | 0*** |
Eos | 79±4 | 0*** | 26±2 | 0*** |
Vessel occlusion (%) | 99.5±0.5 | 7.95±5.8*** | ND | ND |
Collagen deposit (%) | 28.5±2.9 | 3.5±0.4*** | ND | ND |
ND: No determined. ***p<0.001 compared to B6.