TABLE 3.
| Characteristic | All BSI episodes (N=166) | IV epoprostenol (n=66) | IV treprostinil (n=100) | P value |
|---|---|---|---|---|
| Gram-positive organism, No. (%) | 73 (44.0) | 39 (59.1) | 34 (34.0) | .001 |
| Staphylococcus aureus | 46 | 23 | 23 | |
| Staphylococcus epidermidis | 5 | 3 | 2 | |
| Enterococcus species | 5 | 4 | 1 | |
| Corynebacterium jeikeium | 1 | 1 | 0 | |
| Unknown | 6 | 4 | 2 | |
| Otherc | 15 | 7 | 8 | |
| Gram-negative organism, No. (%) | 72 (43.4) | 17 (25.8) | 55 (55.0) | <.001 |
| Pseudomonas aeruginosa | 20 | 2 | 18 | |
| Moraxella catarrhalis | 0 | 0 | 0 | |
| Escherichia coli | 3 | 0 | 3 | |
| Stenotrophomonas maltophilia | 2 | 0 | 2 | |
| Klebsiella oxytoca | 9 | 1 | 8 | |
| Enterobacter cloacae | 10 | 1 | 9 | |
| Unknown | 2 | 1 | 1 | |
| Otherd | 32 | 12 | 20 |
BSI = bloodstream infection; IV = intravenous.
BSIs are not mutually exclusive; >1 infection can be counted per patient, and patients may have >1 organism per BSI episode; thus, the number of organisms may sum to more than the number of total infections.
Other gram-positive organisms included coagulase-negative Staphylococcus such as Staphylococcus epidermidis, Staphylococcus hominis, and Staphylococcus capitis; gram-positive rods such as diphtheroid; Dietzia species; and non anthracis Bacillus species; methicillin-resistant Staphylococcus aureus; Micrococcus species; Candida albicans; and nonhemolytic Streptococcus organisms.
Other gram-negative organisms included Acinetobacter such as Acinetobacter baumannii; serratia such as Serratia marcescens; Brevundimonas vesicularis; Stenotrophomonas species; Roseomonas species; Pseudomonas species such as Pseudomonas fluorescens, Pseudomonas putida, and Pseudomonas luteola; Aeromonas hydrophila; Pantoea species such as Pantoea agglomerans; Enterobacter aerogenes; Klebsiella pneumoniae; Neisseria species; Herbaspirillum species; Salmonella species; Citrobacter freundii; mixed gram-negative flora; and gram-negative rods.