Figure 2. Aerobic capacity (Panel A) and treadmill time (Panel B) at 16 weeks, adjusted for age, gender, ethnicity, and baseline scores of the outcome.

Contrasts were planned and non-orthogonal: Exercise vs. Sertraline and Exercise vs. Placebo, with Bonferroni correction. Thicker horizontal line represents median; thinner, wider line represents mean. Box represents 25^th and 75^th percentiles. Following treatment, Exercise was associated with higher levels of aerobic capacity and longer treadmill time compared to either Sertraline or Placebo (P’s < .001).