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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: J Bone Miner Res. 2012 Dec;27(12):2452–2463. doi: 10.1002/jbmr.1701

Figure 3. PKCδ regulates bone homeostasis in physiological and pathological conditions.

Figure 3

(A) Femurs of 8 week-old WT and PKCδ−/− mice were subjected to μCT analysis to detect trabecular bone. Images show representative 3D reconstructions.

(B) Quantitative analysis of bone parameters were obtained from μCT data. Data are expressed as average +/− standard deviation. An asterisk (*) depicts differences with a p <0.05.

(C) Histomorphometric analysis of the number of osteoclasts per bone surface from sections of 8 week-old mice (n=4/group).

(D) WT and PKCδ−/− female mice were subjected to ovariectomy and trabecular bone volume versus total bone volume (BV/TV) was determined using vital μCT analysis before (pre OVX) and 1 month after ovariectomy (post OVX). Images show representative 3D reconstructions.

(E) Quantitative analysis of percent trabecular bone volume versus total bone volume (n=4/group). An asterisk (*) depicts differences with a p value <0.05.