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. 2012 Jul 24;20(11):2019–2030. doi: 10.1038/mt.2012.134

Figure 5.

Figure 5

Bilateral full-field electroretinographic traces from dogs NA1, A1, A2, and A6 at 1, 9, and 18 months following subretinal injection. (a) Electroretinographic trace from control nonaffected, untreated dog NA1 at 18 months of age. (b) Electroretinographic traces from control affected, untreated dog A1 at 1 and 18 months of age. (c) Electroretinographic traces from dog A2 treated with AAV2/5RK.cpde6β. (d) Electroretinographic traces from dog A6 treated with AAV2/8RK.cpde6β. The top two recordings are low- and high-intensity dark-adapted responses, whereas the bottom two recordings show light-adapted responses (responses to single flash and 30 Hz flicker stimuli, respectively). AAV, adeno-associated virus; mpi, month(s) postinjection; T, treated eye; U, untreated eye.