Table 2.
Neutrophils and mast cells migration profile after prednisolone and nedocromil therapy in the digits
Digits synovial tissue |
|||
---|---|---|---|
Cell Type | Untreated | Prednisolone | Nedocromil |
Neutrophils | 1,512±21.2 | 206±54.1*** | 289±39.4*** |
Intact mast cells | 27.5±1.9 | 203±20.0** | 6.7±1.0*** |
Degranulated mast cells | 12.5±2.3 | 137±10.4*** | 10.6±0.4 |
Data report the number of the specified cell type per mm2 as quantified in digit synovial tissue of arthritic mice on day 32. Mice were either left untreated, or treated with Prednisolone (4 μmol/Kg) or Nedocromil (2 mg/Kg) from day 21 to day 32. Values are mean±s.e.m. of 5 mice pre group.
P<0.01 and
P<0.001 vs untreated arthritic group.