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. Author manuscript; available in PMC: 2012 Nov 15.
Published in final edited form as: Clin Gastroenterol Hepatol. 2008 Sep 3;7(2):192–197. doi: 10.1016/j.cgh.2008.08.031

Table 5.

Effect of Location and Size of Hyperplastic Polyps on Adenoma Recurrence among Participants with 1 or 2 Low-Risk Adenomas at Baseline*

Baseline Characteristics Follow-up colonoscopy findings
Largest size of
hyperplastic
polyps		 Location of
hyperplastic
polyps		 Number of
subjects
(%)		 Any adenoma
recurrence
OR (95% CI)		 Advanced adenoma
recurrence †
OR (95% CI)
No
hyperplastic
polyp		 N/A 598 (74.8) 1.0 (reference) 1.0 (reference)
< 6 mm Distal only 124 (15.5) 1.24 (0.83–1.87) 1.04 (0.37–2.91)
< 6 mm Any proximal 39 (4.9) 0.63 (0.30–1.34) 1.08 (0.28–4.88)
≥ 6 mm Distal only 19 (2.4) 1.36 (0.53–3.51) 1.30 (0.15–11.00)
≥ 6 mm Any proximal 20 (2.5) 1.73 (0.68–4.34) 3.74 (0.74–18.95)
*

For 800 out of 829 participants; 29 participants with missing information on size of hyperplastic polyps were excluded

†

Advanced adenoma = any adenoma with size ≥ 10mm or high-grade dysplasia or villous histology

Multivariable adjustment for age, sex, body mass index and smoking