Table 1.
Demographic and clinical characteristics for the full sample (n = 70) and according to BT status and laterality
| Variable | Full Sample (n = 70), | Benign BT (n = 45), | Malig. BT (n = 25), | t or χ2 | LH Benign (n = 23), | RH Benign (n = 22), | t or χ2 | LH Malig. (n = 11), | RH Malig. (n = 11), | t or χ2 |
|---|---|---|---|---|---|---|---|---|---|---|
| M (SD) | M (SD) | M (SD) | t | M (SD) | M (SD) | t | M (SD) | M (SD) | t | |
| Age, y & mo | 50.57 (14.37) | 54.36 (13.23) | 43.74 (14.03) | 3.09** | 58.35 (12.12) | 50.18 (13.32) | −2.15 | 46.55 (12.67) | 44.96 (15.06) | −0.27 |
| Education, y | 13.77 (3.2) | 13.40 (3.25) | 14.44 (2.96) | −1.32 | 13.70 (3.42) | 13.09 (3.12) | −0.62 | 14.64 (2.20) | 14.18 (3.94) | −0.33 |
| Time since BT diagnosis, mo | 27.62 (60.31) | 29.63 (51.18) | 23.95 (75.06) | 0.38 | 19.42 (30.99) | 40.37 (65.17) | 1.39 | 9.33 (15.06) | 41.44 (112.33) | 0.94 |
| T1: Time prior to RT treatment, days | 15.22 (17.6) | 17.91 (20.23) | 10.48 (10.51) | 2.01 | 21.96 (24.73) | 13.48 (12.96) | −1.41 | 9.09 (8.74) | 11.36 (13.03) | 0.48 |
| T2: Time since RT completion, mo (n = 67) | 3.54 (0.84) | 3.48 (0.85) | 3.64 (0.84) | −0.74 | 3.48 (0.99) | 3.48 (0.68) | −0.01 | 3.47 (0.83) | 3.7 (0.76) | 0.65 |
| RT dosage (Gy) | 44.63 (17.4) | 39.62 (18.46) | 53.47 (11.16) | −3.88** | 38.79 (19.50) | 40.52 (17.67) | 0.31 | 52.84 (13.44) | 53.76 (10.63) | 0.18 |
| Fractionated treatment (Gy) | [n = 34] | |||||||||
| 47.06 (13.84) | 53.47 (11.16) | −1.90 | ||||||||
| n (%) | n (%) | n (%) | χ2/p | n (%) | n (%) | n (%) | n (%) | |||
| Gender | ||||||||||
| Male | 32 (46) | 17 (38) | 15 (47) | 3.20 | 8 (35) | 9 (41) | 7 (64) | 5 (55) | ||
| Female | 38 (54) | 28 (62) | 10 (40) | 15 (65) | 13 (59) | 4 (36) | 6 (45) | |||
| Age group | ||||||||||
| <65 y (younger) | 56 (80) | 33 (73) | 23 (92) | NA | 15 (65) | 18 (82) | 10 (91) | 10 (91) | ||
| ≥65 y (older) | 14 (20) | 12 (27) | 2 (8) | 8 (35) | 4 (18) | 1 (9) | 1 (9) | |||
| Education | ||||||||||
| <High school | 18 (26) | 14 (31) | 4 (16) | NA | 7 (31) | 7 (32) | 1 (9) | 3 (27) | ||
| High school | 9 (13) | 6 (13) | 3 (12) | 4 (17) | 2 (9) | 1 99) | 1 (9) | |||
| Graduate degree | 43 (61) | 25 (56) | 8 (72) | 12 (52) | 13 (59) | 7 (64) | 7 (64) | |||
| Marital status | ||||||||||
| Married/partnered | 52 (74) | 33 (73) | 19 (76) | NA | 15 (65) | 18 (82) | 11 (100) | 7 (64) | ||
| Single (incl. separated/divorced) | 18 (26) | 12 (27) | 6 (24) | 8 (35) | 4 (18) | 0 (0) | 4 (36) | |||
| Employment status | ||||||||||
| Not working | 39 (56) | 27 (60) | 12 (48) | 0.94 | 14 (61) | 13 (59) | 5 (45) | 5 (45) | ||
| Working | 31 (44) | 18 (40) | 13 (52) | 9 (39) | 9 (41) | 6 (55) | 6 (55) | |||
| Type of treatments received | ||||||||||
| 1 treatment | 26 (37) | 24 (53) | 2 (8) | NA | 12 (52) | 12 (54) | 1 (9) | 1 (9) | ||
| >1 treatment | 44 (63) | 21 (47) | 23 (92) | 11 (48) | 10 (46) | 10 (91) | 10 (91) | |||
| RT | ||||||||||
| Fractionated | 60 (86) | 35 (78) | 25 (100) | NA | 17 (74) | 18 (82) | 11 (100) | 11 (100) | ||
| Stereotactic (single dose; IMRS) | 10 (14) | 10 (22) | 0 (0) | 6 (26) | 4 (18) | 0 (0) | 0 (0) | |||
| Types of medical treatments | ||||||||||
| RT only | 26 (37) | 24 (35) | 2 (8) | NA | 12 (52) | 12 (55) | 1 (9) | 1 (9) | ||
| Presurgical + RT | 34 (49) | 21 (47) | 13 (52) | 11 (48) | 10 (46) | 6 (55) | 4 (36) | |||
| Presurgical + RT+ | 10 (14) | 0 (0) | 10 (40) | 0 (0) | 0 (0) | 4 (36) | 6 (55) | |||
| chemotherapy | ||||||||||
| Medication usage, yes | 43 (61) | 26 (58) | 17 (68) | 0.71 | 17 (74) | 9 (41) | 8 (73) | 8 (73) | ||
| Anticonvulsants | 15 (21) | 5 (11) | 10 (40) | 8.00** (P = .007) | 3 (13) | 2 (9) | 4 (36) | 5 (46) | ||
| Pain medication | 6 (9) | 5 (11) | 1 (4) | NA | 4 (18) | 1 (5) | 0 | 1 (9) | ||
| Concurrent medical conditions, yes | 43 (61) | 29 (64) | 14 (56) | 0.48 | 18 (78) | 11 (50) | 7 (64) | 7 (64) | ||
| Family history of cancer, yes | 45 (65) | 26 (59) | 19 (76) | 2 | 15 (65) | 11 (52) | 9 (82) | 9 (82) | ||
| History of psychological problems, yes | 24 (35) | 11 (26) | 13 (52) | 4.83* (P = .037) | 9 (41) | 2 (10) | 5 (46) | 6 (55) | ||
| Stress as cause of BT, yes | ||||||||||
| BT-related problems (ongoing at T2) (n = 65) | 50 (77) | 31 (74) | 19 (83) | 0.65 | 18 (82) | 13 (65) | 8 (80) | 8 (80) | ||
| Major stressors at T2 (n = 65) | 35 (54) | 23 (55) | 12 (52) | 0.04 | 13 (59) | 10 (50) | 5 (50) | 5 (50) | ||
Abbreviations: RT, radiotherapy; IMRS, intensity-modulated radiosurgery.
*Statistically significant at P < .05.
**Statistically significant at P < .01.