. 2012 Oct 11;14(12):1485–1502. doi: 10.1093/neuonc/nos244

Table 2.

Psychosocial and neurocognitive functioning at T1 and T2 according to BT diagnosis: benign vs malignant tumor

	Benign, M (SE)	Malignant, M (SE)	Main Effect Observed P	Signature Adjusted P (<.003)	Between- Groups Observed P	Signature Adjusted P (<.003)	Benign Within- Group Observed P (adjusted) (<.003)	Malignant Within- Group Observed P (adjusted) (<.003)
Psychosocial variables
PCL-S^a
T1	29.3 (1.9)	29.1 (2.6)			.965	NS
T2	24.8 (1.4)	29.1 (1.8)	.067	NS	.065	NS	.003^#	.982
N	44	23
IES^a total
T1	20.8 (2.5)	19.4 (3.5)			.762	NS
T2	12.9 (2.3)	21.7 (3.2)	.093	NS⁺⁺	.025	NS	.000**	.399
N	44	23
FACT-PWB
T1	22.7 (0.7)	21.9 (1.1)			.533	NS
T2	22.9 (0.8)	21.5 (1.1)	.959	NS	.315	NS	.764	.783
N	44	22
FACT-SWB
T1	22.6 (0.6)	23.0 (0.9)			.727	NS
T2	22.0 (0.7)	20.7 (1.0)	.008	TR^#	.273	NS	.349	.009^#
N	44	22
FACT-EWB
T1	17.7 (0.7)	16.3 (1.0)			.267	NS
T2	19.4 (0.7)	15.7 (1.0)	.4	NS	.003	TR^#	.031	.605
N	44	22
FACT-FWB
T1	21.3 (0.8)	19.8 (1.1)			.271	NS
T2	21.4 (0.8)	18.5 (1.2)	.466	NS	.055	NS	.826	.295
N	44	22
FACT-G total
T1	84.1 (2.0)	80.9 (2.8)			.345	NS
T2	85.8 (2.3)	76.5 (3.2)	.421	NS	.022	NS	.412	.120
N	44	22
FACT-Br
T1	59.6 (1.7)	56.8 (2.5)			.366	NS
T2	59.9 (1.6)	53.9 (2.3)	.252	NS	.039	NS	.780	.112
N	44	22
POMS depression^a
T1	39.2 (1.2)	40.7 (1.7)			.465	NS
T2	37.9 (1.0)	42.0 (1.4)	.967	NS	.019	NS	.329	.458
N	44	22
POMS anger^a
T1	43.9 (1.2)	46.7 (1.7)			.171	NS
T2	43.1 (0.9)	45.0 (1.3)	.212	NS	.238	NS	.495	.294
N	44	22
POMS vigor^a
T1	57.8 (1.7)	61.6 (2.2)			.159	NS
T2	57.2 (1.7)	59.9 (2.4)	.434	NS	.36	NS	.732	.474
N	44	22
POMS fatigue^a
T1	45.9 (1.3)	48.6 (1.9)			.249	NS
T2	46.6 (1.5)	50.4 (2.1)	.274	NS	.144	NS	.587	.338
N	44	22
POMS confusion^a
T1	41.8 (1.3)	43.1 (1.8)			.54	NS
T2	40.9 (1.2)	43.6 (1.7)	.828	NS	.204	NS	.441	.78
N	44	22
PRCI positive support
T1	46.76 (1.7)	51.50 (2.4)			.109
T2	43.78 (1.7)	47.00 (2.3)	.012		.269	NS	.086	.058
N	41	22		NS		NS
SCS friends/family^a
T1	.56 (0.1)	.69 (0.2)			.521	NS
T2	.49 (0.1)	.67 (0.1)	.608	NS	.253	NS	.463	.916
N	43	22
SCS spouse/partner^a
T1	.46 (0.1)	.55 (0.2)			.664	NS
T2	.36 (0.1)	1.03 (0.2)	.048	NS⁺⁺	.002	**	.367	.003^#
N	43	22
Neurocognitive tests (signature adjusted P < .006)
LM I recall^b
T1	9.7 (0.5)	10.3 (0.7)			.508	NS
T2	11.4 (0.6)	11.4 (0.8)	.001	*	.995	NS	.001*	.092
N	42	23
LM II recall^b
T1	10.0 (0.6)	10.0 (0.8)			.982	NS
T2	12.2 (0.6)	11.0 (0.8)	.000	*	.245	NS	.000*	.092
N	42	23
LM II retention^b
T1	10.8 (0.6)	9.4 (0.8)			.187	NS
T2	12.7 (0.5)	11.0 (0.6)	.000	*	.025	NS	.000*	.033
N	42	23
Digit Span^b
T1	10.5 (0.5)	11.2 (0.7)			.424	NS
T2	11.3 (0.5)	11.2 (0.7)	.325	NS	.923	NS	.098	1.00
N	43	23
Similarities^b
T1	10.8 (0.5)	10.9 (0.7)			.916	NS
T2	10.7 (0.6)	12.6 (0.9)	.011	NS	.086	NS	.794	.001*
N	43	21
COWAT^c
T1	35.2 (4.1)	27.0 (5.5)			.233	NS
T2	41.0 (4.3)	30.0 (5.8)	.082	NS	.132	NS	.057	.447
N	42	23
TMT-A^c
T1	52.7 (5.6)	44.4 (6.2)			.326	NS
T2	63.6 (5.7)	48.9 (6.3)	.053	NS	.089	NS	.041	.44
N	22	18
TMT-B^c
T1	24.1 (5.5)	27.8 (6.1)			.658	NS
T2	40.5 (7.0)	35.0 (7.8)	.024	NS	.606	NS	.02	.339
N	22	18

Abbreviations: NS, not significant at adjusted P values; TR, statistical significant trend; Sig. = Statistical Significance (with adjusted P value

^aHigh score denotes poorer performance; for all other scores, the reverse applies.

^bAge-matched scaled scores used according to validated Wechsler manuals.

^cPercentile scores calculated on age and gender according to validated norms.

*Neurocognitive tests adjusted P < .006.

**Psychosocial variables adjusted P < .003.

^#Psychosocial and neurocognitive variables significant trend P < .01.

⁺⁺Significant interaction effect: IES total, P = .003; SCS spouse, P = .003.