Table 1.
Total | MGMT |
ALDH1A1 |
|||||||
---|---|---|---|---|---|---|---|---|---|
Methylation |
No methylation |
≤ 10 % |
> 10 % |
||||||
no. | no. | % | no. | % | no. | % | no. | % | |
Patients | 70 | 17 | 24.3 | 53 | 75.7 | 42 | 60 | 28 | 40 |
Treatment | |||||||||
standard* | 50 | 13 | 18.6 | 37 | 52.9 | 33 | 47.1 | 17 | 24.3 |
others** | 20 | 4 | 5.7 | 16 | 22.9 | 9 | 12.9 | 11 | 15.7 |
Sex | |||||||||
men | 50 | 13 | 18.6 | 37 | 52.9 | 31 | 44.3 | 19 | 27.1 |
women | 20 | 4 | 5.7 | 16 | 22.9 | 11 | 15.7 | 9 | 12.9 |
Age***(years) | |||||||||
≤ 60 | 28 | 7 | 10 | 21 | 30 | 21 | 30 | 7 | 10 |
61–70 | 27 | 6 | 8.6 | 21 | 30 | 14 | 20 | 13 | 18.6 |
> 70 | 15 | 4 | 5.7 | 11 | 15.7 | 7 | 10 | 8 | 11.4 |
*Therapeutic regimen described by Stupp et al.1
**Resection plus radiotherapy, radiotherapy and concomitant TMZ, or adjuvant TMZ.
***Age of the patients when diagnosed.