Table V.
Parameter | Estimate | Estimate 95% CI |
χ2 | P | FR (95% CI) | |
Lower | Upper | |||||
Intercept | 1.89 | 1.36 | 2.40 | 50.70 | <0.001 | — |
Cumulative exposure dose (mg) | ||||||
<4000 (ref. group) | — | — | — | — | — | — |
4000–40 000 | 0.18 | 0.06 | 0.30 | 8.96 | 0.003 | 1.19 (1.06–1.34) |
>40 000 | 0.16 | 0.01 | 0.30 | 4.62 | 0.03 | 1.17 (1.01–1.35) |
GSTP1 Ile105Val (Ile) | −0.31 | −0.53 | −0.07 | 6.69 | 0.01 | 0.74 (0.59–0.94) |
CYP2E1 c1/c2 (c2) | 0.11 | 0.02 | 0.21 | 5.47 | 0.02 | 1.12 (1.02–1.23) |
ALDH2 Glu504Lys (Lys) | −0.14 | −0.24 | −0.05 | 8.74 | 0.003 | 0.87 (0.79–0.95) |
XRCC1 Arg280His (Arg) | 0.12 | 0.02 | 0.22 | 5.23 | 0.02 | 1.13 (1.02–1.25) |