Table 3.

Rankings with respect to TI for parameter amplification ([1.1–2, 3–10]-fold of each parameter’s reference value)

Rankings	Parameter	Variation	TI	Cell number		Simulation step
Group I
1	ERK	1.1	0.1843	13682	↓	222	—
2	TGFβR	3	0.1756	13828	↓	222	—
3	Ras	4	0.0161	16503	↓	222	—
4	PKC	2	0.0024	16732	↓	222	—
Group II
1	PLCγ	6	0.7395	214	↓	167	↓
2	EGFR	10	0.7111	766	↓	168	↓
3	MEK	10	0.4678	5829	↓	181	↓
4	ERK	1.2	0.2518	11417	↓	207	↓
5	TGFβR	10	0.184	13535	↓	220	↓
6	Raf	3	0.0253	16198	↓	220	↓
7	PKC	1.2–1.3	− 0.0001	16775	↑	222	—