Table 1.
Physical parameters of the IBCell model of acinar morphogenesis
| Model parameter | Value | Units | References |
|---|---|---|---|
| Fluid density | ρ = 1.35 | g/cm3 | Dembo & Harlow (1986) |
| Laurent et al. (2003) | |||
| Fluid viscosity | μ = 100 | g/(cm · s) | Dembo & Harlow (1986) |
| Laurent et al. (2003) | |||
| Elastic membrane force stiffness | ℱelastic = 500 | g/(cm · s) | Laurent et al. (2003) |
| Adhesive force stiffness | ℱadhesive = ℱelastic | g/(cm · s) | Rejniak & Anderson (2008a) |
| Contractile force stiffness | ℱcontractile = 50 × ℱelastic | g/(cm · s) | Rejniak & Anderson (2008a) |
| Fluid sources and sinks | 𝒮+ = 𝒮− =5 × 10−10 | g/s | Rejniak & Anderson (2008a) |
| Elastic spring resting length | ℒelastic = 0.5 | μm | Rejniak & Anderson (2008a) |
| Adhesive spring resting length | ℒadhesive = 0.5 | μm | Rejniak & Anderson (2008a) |
| Contractile spring resting length | ℒcontractile = 2.5 | μm | Rejniak & Anderson (2008a) |
| ECM secretion rate (at the growth receptors) | κ1 = 1 × 10−10 | mM/s | This text |
| ECM decay rate | κ2 = 0.05 × κ1 | 1/s | This text |