Table 2.
In vitro maturation outcome of PCOS women with or without hCG-priming
| hCG-primed group | Non-primed group | p | |
|---|---|---|---|
|
No. of oocyte retrieval cycles |
40 |
42 |
|
|
No. of oocytes retrieved |
|
|
|
| Total (range) |
552 (1–50) |
603(1–47) |
|
| Mean |
13.80 |
14.35 |
ns |
|
No. of oocytes matured at 32 h |
|
|
|
| Total (range) |
306 (1–21) |
255 (0–18) |
|
| Mean |
7.65 |
6.07 |
|
| Maturation rate (%) |
55.43 |
42.29 |
0.000 |
|
No. of oocytes fertilized (%) |
194 (63.40) |
167 (65.49) |
ns |
|
No. of oocytes cleaved (%) |
192 (98.97) |
166 (99.10) |
ns |
|
Cycles with embryo transfer (%) |
34 (85.0) |
40 (95.24) |
ns |
|
No. of embryos transferred (mean) |
70 (2.06) |
86 (2.15) |
ns |
|
No. of clinical pregnancies |
15 |
21 |
|
| Clinical pregnancy rate per ORa(%) |
37.50 |
50.00 |
ns |
| Clinical pregnancy rate per ETb(%) |
44.12 |
52.50 |
ns |
|
No. of embryos implantation (%) |
23 (32.86) |
28 (32.56) |
ns |
|
No. of live birth (% per OR) |
9 (22.50) |
13 (30.95) |
ns |
| Singleton |
5 |
11 |
|
| Twins |
4 |
2 |
|
|
No. of infants |
13 |
15 |
|
|
No. of miscarriage (%)c |
6 (40.00) |
8 (38.10) |
ns |
| Early miscarriage (<12 weeks) |
3 |
5 |
|
| Late miscarriage (12–28 weeks)d |
3 |
3 |
|
| No. of cycles with embryo freezing | 19 (47.50) | 13 (30.95) | ns |
aOR oocyte retrieval.
bET embryo transfer.
c Miscarriage was defined as pregnancy loss after ultrasonographic evidence of an intrauterine pregnancy.
d Late miscarriage was defined as pregnancy loss between 12 and 28 weeks of gestation, which includes any termination of pregnancy after diagnosis of a congenital abnormality.