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. 2012 Oct 3;7(1):549. doi: 10.1186/1556-276X-7-549

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Copyright ©2012 Azizian et al.; licensee Springer.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Longitudinal(R₁)(a)and transversal(R₂)(b)relaxation rates vs. concentration. The slope of the curve or relaxivity (r₁ and r₂) was obtained for Gd-DTPA (diamond), Gd₂O₃-DEG (square), SPGO-mPEG-silane550 (triangle), and SPGO-mPEG-silane2000 (cross). The solid lines represent the linear regression of the data. Gd₂O₃-DEG had longitudinal proton relaxivity at least 2.5 times higher than Gd-DTPA, whereas r₁ for SPGO-mPEG-silane550 and 2000 was less compared with Gd-DTPA.