Skip to main content
. 2012 Nov 15;8(11):e1003028. doi: 10.1371/journal.pgen.1003028

Figure 1. Pol II and III occupancy of snRNA genes.

Figure 1

(A) Bar graph showing POLR2B (dark blue), GTF2B (light blue), POLR3D (red), and BRF2 (orange) ChIP-seq scores (y axis) on SNAPc-occupied genes and the few snRNA genes devoid of SNAPc (x axis). Genes are ordered by decreasing POLR2B scores for the pol II and RPPH1 genes followed by increasing POLR3D scores for the pol III genes. (B) UCSC browser view of RPPH1 gene showing POLR2B, POLR3D, GTF2B, and BRF2 occupancy. Y axis: tag counts. (C) POLR2B (light grey) or POLR3D (dark grey) occupancy in cells not treated or treated with 50 µg/ml α-amanitin for 2 or 6 h, as indicated on the x axis. Upper two panels: results are shown as % of input. Lower two panels: POLR2B and POLR3D occupancy without α-amanitin was set at 1.