Table 1. Dopamine receptors DOP-2 and DOP-3 mediate DA inhibition of ARE-induced protraction.
| Genotype | % Males protracted (n) | P-value Fisher's exact test | ||
| ARE (1 mM) | DA(30 mM) +ARE(1 mM) | DA(20 mM) +ARE(1 mM) | ||
| Wild type | 94 (61) | 14 (117) | ND | |
| dop-1 (vs100) | 75 (24) | 20 (25) | ND | NS* |
| dop-2 (vs105) | 92 (50) | 58 (101) | ND | P<0.0001* |
| dop-3 (vs106) | 90 (30) | 59 (32) | ND | P = 0.0006* |
| dop-4 (tm1392) | 93 (31) | 26 (26) | ND | NS* |
| dop-2 ; dop-3 | 95 (76) | 54 (85) | 63 (40) | P = 0.005* |
| lgc-53 (n4330) | 72 (25) | ND | 16 (25) | NS* |
| dop-2 ; pha-1 | 95 (20) | ND | 48 (52) | |
| dop-3 ; pha-1 | 100 (19) | ND | 47 (40) | |
| dop-2 rgEx462 [Paex-3:dop-2::CFP] | 86 (30) | ND | 43 (48) | NS** |
| dop-2 rgEx467 [Punc-103E:dop-2::CFP] | 86 (30) | ND | 15 (51) | P = 0.0002** |
| dop-3 rgEx490 [Paex-3:dop-3::YFP] | 95 (20) | ND | 24 (37) | NS** |
| dop-3 rgEx482 [Punc-103E:dop-3::YFP] | 90 (20) | ND | 7 (39) | P = 0.001** |
*
Compared with wild-type DA+ARE sensitivity.
**
Compared with mutants DA+ARE sensitivity in a pha-1 background sensitivity.
All transgenic animals contain pha-1(lf).