Table 1. Characterization of GPC3 expression in non-HCC in the NCI-60 set.
| Human cell line | Tumor type | Gene expression (microarray)* | Protein expression (immunoblotting)@ | Surface expression (flow cytometry) @ |
|---|---|---|---|---|
| NCI-H522 |
Non-Small Cell Lung Cancer |
+++ |
+++ |
+/− |
| MALME-3M |
Melanoma |
++ |
- |
- |
| SK-MEL-5 |
Melanoma |
++ |
+ |
+/− |
| UACC-62 |
Melanoma |
++ |
+++ |
+ (histogram shown in Figure 2A) |
| IGROV-1 |
Ovarian cancer |
++ |
++ |
- |
| OVCAR-8 |
Ovarian cancer |
++ |
+ |
- |
| NCI-ADR-RES | Ovarian cancer | ++ | +++ | +/− |
*
http://dtp.nci.nih.gov/mtweb; @ probed by YP7