Table 3. The 30 most significantly associated probes in DNA from female subjects.
| |
|
|
|
Average β values for each usage class |
|||
|---|---|---|---|---|---|---|---|
| Probe ID | GENE | Placement | Island status | None | Light | T-test | Corrected p value |
| cg11685249 |
TSSK1B |
TSS1500 |
|
0.817 |
0.740 |
2.85E-07 |
0.09 |
| cg05575921 |
AHRR |
Body |
N Shore |
0.904 |
0.864 |
4.51E-07 |
0.09 |
| cg06961873 |
TMEM57 |
3′UTR |
|
0.716 |
0.510 |
2.35E-06 |
0.32 |
| cg12500300 |
|
|
|
0.719 |
0.560 |
3.18E-06 |
0.33 |
| cg01038172 |
|
|
Island |
0.709 |
0.667 |
4.32E-05 |
0.81 |
| cg21085686 |
|
|
N Shelf |
0.761 |
0.721 |
4.74E-05 |
0.81 |
| cg06875704 |
MIR510 |
TSS1500 |
|
0.868 |
0.801 |
4.89E-05 |
0.81 |
| cg22159835 |
NRXN2 |
Body |
|
0.766 |
0.722 |
4.95E-05 |
0.81 |
| cg06768670 |
|
|
|
0.843 |
0.824 |
5.12E-05 |
0.81 |
| cg14611816 |
BAIAP2 |
Body |
|
0.511 |
0.460 |
6.73E-05 |
0.81 |
| cg16879197 |
C4orf50 |
Body |
|
0.808 |
0.734 |
6.99E-05 |
0.81 |
| cg10328548 |
SS18L1 |
Body |
S Shore |
0.897 |
0.825 |
7.04E-05 |
0.81 |
| cg06578276 |
BAIAP2 |
Body |
|
0.514 |
0.463 |
7.96E-05 |
0.81 |
| cg14696820 |
LCE1A |
1stExon |
|
0.651 |
0.614 |
8.54E-05 |
0.81 |
| cg06619428 |
LCE2B |
3′UTR |
|
0.671 |
0.629 |
9.38E-05 |
0.81 |
| cg03640465 |
SLC2A9 |
TSS1500 |
|
0.866 |
0.823 |
0.0002 |
0.81 |
| cg01177709 |
COMMD8 |
Body |
N Shore |
0.514 |
0.471 |
0.0002 |
0.81 |
| cg08276328 |
MAGEC1 |
TSS1500 |
|
0.698 |
0.675 |
0.0002 |
0.81 |
| cg00848461 |
PRELID1 |
Body |
S Shore |
0.690 |
0.632 |
0.0002 |
0.81 |
| cg23268879 |
TNRC18 |
Body |
N Shore |
0.885 |
0.866 |
0.0002 |
0.81 |
| cg06587435 |
|
|
N Shore |
0.761 |
0.696 |
0.0002 |
0.81 |
| cg02716826 |
SUGT1P1 |
Body |
N Shore |
0.399 |
0.363 |
0.0002 |
0.81 |
| cg11124142 |
LOC100129055 |
TSS1500 |
|
0.727 |
0.699 |
0.0002 |
0.81 |
| cg13632983 |
|
|
S Shelf |
0.689 |
0.658 |
0.0002 |
0.81 |
| cg27348515 |
ARMCX2 |
TSS200 |
|
0.331 |
0.359 |
0.0002 |
0.81 |
| cg09083945 |
BAIAP2 |
Body |
|
0.401 |
0.363 |
0.0002 |
0.81 |
| cg12873476 |
|
|
S Shore |
0.760 |
0.730 |
0.0002 |
0.81 |
| cg10978503 |
CNR2 |
3′UTR |
|
0.804 |
0.767 |
0.0002 |
0.81 |
| cg00294152 |
|
|
|
0.686 |
0.637 |
0.0002 |
0.81 |
| cg21854924 | MIR510 | TSS200 | 0.548 | 0.464 | 0.0002 | 0.81 | |
All average methylation values are non-log transformed β-values. Island status refers to the position of the probe relative to the island. Classes include: (1) Island, (2) N (north) shore, (3) S (south) shore, (4) N (north shelf), (5) S (south) shelf and (6) blank denoting that the probe does not map to an island.