Figure 2. (A) Electropherogram of rat serum samples (two animals) dosed with labeled mAb and analyzed at various time points (0.25 h to day 28) (B) Digital gel image after serial dilution of labeled mAb spiked into rat serum in vitro, and analysis of rat serum samples from PK study with labeled antibody after a 1:10 dilution in denaturation buffer.