Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Aug 7;5:12. doi: 10.1186/1756-8935-5-12

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright ©2012 Prickaerts et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

MK3 is a negative regulator of ERK.(A,D) mRNA expression of PRC1 target gene ATF3 as a function of kinase inhibition (A) or MK3OE(D) in TIG3 cells. (B,C, E, F) (p)ERK (B), (p)P38 (C), H3S28ph (E) and (p)MEK (F) levels in starved and stimulated U2-OS cells in relation to MK function; t (min): time post-stimulation in minutes; *: loading controls for corresponding panels; t+: longer exposure. Samples corresponding to control and experiment (MK3OE or MKi) were always loaded on the same gel to enable direct quantitative analysis (corresponding sections are shown separately; representative experiment shown; quantification pERK profiles: compare Additional file 3: Figure S3B). (G) Mitogen-induced DUSP2 and DUSP5-mRNA in control, MK3OE and MKi TIG3 cells.