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. 2012 Nov 15;7(11):e49653. doi: 10.1371/journal.pone.0049653

Figure 2. Expression levels of inflammatory genes in infected EPCs. A.

Figure 2

Expression levels of 84 inflammatory genes in EPCs infected with B. henselae, B. fragilis, B. fragilis ΔPSA, B. henselae and B. fragilis, B. henselae and B. fragilis ΔPSA. Differential expression data are evaluated vs uninfected EPCs. B. Bar graph showing the expression of some relevant differentially expressed genes encoding chemokines, cytokines and their receptors in B. fragilis- vs B. fragilis ΔPSA-infected EPCs. Data are shown as relative expression levels (B. fragilis ΔPSA-infected cells = 1). C. and D. Expression levels of representative pro-inflammatory (C) and anti-inflammatory (D) genes highly differentially expressed during coinfection of EPCs, in presence and in absence of PSA. E. and F. Absolute quantification of relevant secreted inflammatory proteins detected by ELISA in the EPCs infected with B. henselae, and coinfected with B. fragilis and B. fragilis ΔPSA.