Figure 1. Etanercept significantly delays the progression of hepatic encephalopathy in mice with AOM-induced ALF.

Time to coma (loss of corneal reflex) in ALF mice treated with etanercept (ETA) 30 min prior to, or 3 h and 6 h after AOM treatment. Data represent mean ± SEM of n = 6 animals in each group. *p<0.001 vs. Saline.