Table 1. Effect of azoxymethane (AOM) on plasma transaminase activities, ammonia, TNF-α and IL-6 levels over time.

	Control	3 h	6 h	9 h	12 h	Coma
AST (U/L)	176.7±31.8	275.0±65.1	303.3±65.7	792.5±207.1	1488±736.6	3113±380.3*
ALT (U/L)	53.3±3.3	57.5±4.8	104.0±24.3	120.0±12.2	312.8±96.2	4733±676.3*
Ammonia (µM)	86.7±15.8	88.9±19.1	133.3±28.4	223.9±10.4	223.9±20.1	577.8±93.0*
TNF-α (pg/mL)	10.8±0.4	21.0±1.5	46.2±2.9	137.1±2.5*	143.7±11.09*	120.4±15.5*
IL-6 (pg/mL)	12.4±4.3	65.4±10.6	803.7±129.5	8568±1174*	6213±1266*	10609±653.1*

Mice (n = 5) were sacrificed at various time points indicated following AOM injection.

^*p<0.001 vs. control by ANOVA.