Table 2. Effects of etanercept on plasma transaminase activities and ammonia levels.

	Control	AOM-induced ALF
		Vehicle-treated	Etanercept-treated
AST (U/L)	112.9±8.0	3674±306.5*	1093±190.1†
ALT (U/L)	64.5±3.9	3699±397.6*	390.0±74.8†
Ammonia (µM)	101.4±5.3	500.4±70.4*	129.5±12.0†

Mice were administered etanercept 30 min prior to azoxymethane (AOM) or saline (Vehicle). Control mice received only saline. Data represent mean ± SEM of n = 12 in each group.

^*p<0.001 vs. Control;

^†p<0.001 vs. vehicle-treated.