Table 3. The binding values of I1 and I2 imidazoline receptors of reference compounds.
nH | Ki(M) | IC50(M) | Assay/Reference compound |
0.9 | 8.4E-08 | 1.6E-07 | I1/rilmenidine |
1.7 | 1.0E-08 | 1.6E-08 | I2/idazoxan |
The IC50,Ki and nHvalues were calculated as described in Materials and Methods.