Figure 3. ABCG2 is differentially expressed in the red blood cells of individuals carrying homozygous wild-type, heterozygous polymorphic or premature stop codon mutant ABCG2 alleles.

Boxplot presentation showing the median and the 25–75^th percentiles, whiskers represent 10–90^th percentiles. ABCG2 expression is calculated based on the combined reactivity of anti-ABCG2 mAbs (RBC-G2 factor – see Methods). Labels: individuals carrying wild-type ABCG2 (WT), polymorphic (Q141K, V12M) ABCG2 alleles, or a heterozygous stop mutation (STOP).