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. 2012 Nov 15;8(11):e1003024. doi: 10.1371/journal.ppat.1003024

Figure 2. 2-AA pretreatment modulates the pro-inflammatory response in vivo.

Figure 2

Multiplex ELISA showed that BI induced surges in serum levels of IL-1α, IL-1β, IL-4, IL-10, IFN-γ, and TNF-α 24 h post-BI, and that 2-AA pretreatment delivered 4 d before BI attenuated the surges in IL-1α, IL-1β, IL-4, IFN-γ, and TNF-α, while augmenting the surge in IL-10 (n = 4 per group). Mean values calculated from 2–4 replicate experiments are depicted with SD error bars. *p<0.05 vs. naïve; **p<0.05 vs. BI (Student's t test).