Table 2.
Association between colorectal cancer-specific mortality and all-cause mortality across pre-diagnostic levels of total recreational physical activity and body mass index
| Colorectal Cancer-Specific Mortality | All-cause Mortality | |||||
|---|---|---|---|---|---|---|
| Deaths/ Cases |
Crude adjusteda HR (95% CI) |
Multivariable- adjustedb HR (95% CI) |
Deaths/ Cases |
Crude adjusteda HR (95% CI) |
Multivariable- adjustedb HR (95% CI) |
|
| Total MET-hours/week physical activity from recreational activities and walking at baseline** | ||||||
| 0 | 34/234 | 1.00 | 1.00 | 53/234 | 1.00 | 1.00 |
| >0–2.9 | 24/166 | 1.06 (0.63–1.78) | 0.98 (0.58–1.66) | 36/166 | 1.02 (0.67–1.56) | 0.93 (0.61–1.43) |
| 3.0–8.9 | 50/350 | 1.03 (0.67–1.60) | 1.01 (0.65–1.57) | 81/350 | 1.04 (0.73–1.47) | 1.01 (0.71–1.43) |
| 9.0–17.9 | 34/312 | 0.85 (0.54–1.34) | 0.74 (0.46–1.20) | 54/312 | 0.76 (0.52–1.11) | 0.77 (0.52–1.12) |
| ≥18.0 | 29/277 | 0.69 (0.42–1.12) | 0.68 (0.41–1.13) | 41/277 | 0.61 (0.41–0.92) | 0.63 (0.42–0.96) |
| Ptrend | 0.08 | 0.08 | 0.006 | 0.02 | ||
| BMI, kg/m2 at baselinec | ||||||
| 18.5–24.9 | 53/412 | 1.00 | 1.00 | 77/412 | 1.00 | 1.00 |
| 25.0–29.9 | 51/472 | 0.82 (0.56–1.21) | 0.77 (0.52–1.13) | 84/472 | 0.90 (0.66–1.23) | 0.84 (0.61–1.14) |
| ≥30.0 | 67/455 | 1.21 (0.84–1.74) | 1.17 (0.80–1.70) | 104/455 | 1.28 (0.95–1.73) | 1.19 (0.88–1.62) |
| Ptrend | 0.27 | 0.39 | 0.08 | 0.22 | ||
a
Adjusted for age and study arm
b
Adjusted for age at diagnosis, study arm, BMI, tumor stage, ethnicity, education, alcohol, smoking, and hormone therapy use
c
Also adjusted for pre-diagnostic physical activity