. Author manuscript; available in PMC: 2013 Dec 1.

Published in final edited form as: Cancer Causes Control. 2012 Sep 28;23(12):1881–1891. doi: 10.1007/s10552-012-0024-9

Table 3.

Adjusted associations between sex steroid hormones, SHBG and body size measurements in the NHANES survey, 1999-2004.

	Total bone area (cm²) per 100 cm² increase			Total bone mineral content (BMC) (g) per 100 g increase			Total bone mineral density (g/cm²)			Fat mass (g) per 1 kg increase			Lean mass excluding BMC (g) per 1 kg increase
	Beta^a	SE	p	Beta^a	SE	p	Beta^a	SE	p	Beta^a	SE	p	Beta^a	SE	p
Testosterone (ng/mL)	-0.12	0.03	< 0.01	-0.04	0.01	< 0.01	-0.97	0.65	0.14	-0.09	0.01	< 0.01	-0.06	0.01	< 0.01
Free testosterone (pg/mL)	-2.81	0.57	< 0.01	-0.83	0.33	0.02	-8.18	15.63	0.60	-1.14	0.16	< 0.01	-0.77	0.13	< 0.01
SHBG (nmol/L)	-0.43	0.35	0.23	-0.35	0.14	0.02	-17.16	6.00	0.01	-0.59	0.06	< 0.01	-0.47	0.06	< 0.01
3-alpha-diol-G (ng/mL)	0.20	0.12	0.11	0.10	0.06	0.09	4.06	2.30	0.09	0.05	0.03	0.06	0.06	0.02	0.03
Estradiol (pg/mL)	0.16	0.27	0.56	0.14	0.13	0.28	7.72	5.46	0.17	0.13	0.08	0.13	0.11	0.08	0.14
Free estradiol (fg/mL)	4.00	8.16	0.63	4.52	3.98	0.26	265.71	171.32	0.13	7.55	2.58	0.01	6.08	2.40	0.02

	Total mass (lean mass + fat mass) (g) per 1 kg increase			Percent body fat (%)			Standing Height (cm) per 10 cm increase			Body mass index (BMI) (kg/m²)			Waist circumference (cm)
	Beta^a	SE	p	Beta^a	SE	p	Beta^a	SE	p	Beta^a	SE	p	Beta^a	SE	p

Testosterone (ng/mL)	-0.04	<0.01	< 0.01	-0.16	0.01	< 0.01	-0.06	0.13	0.65	-0.15	0.02	< 0.01	-0.06	0.01	< 0.01
Free testosterone (pg/mL)	-0.53	0.08	< 0.01	-1.96	0.29	< 0.01	-4.32	2.44	0.08	-1.76	0.30	< 0.01	-0.77	0.12	< 0.01
SHBG (nmol/L)	-0.29	0.03	< 0.01	-1.11	0.11	< 0.01	1.78	1.09	0.11	-1.20	0.12	< 0.01	-0.48	0.04	< 0.01
3-alpha-diol-G (ng/mL)	0.03	0.01	0.03	0.07	0.04	0.11	0.23	0.23	0.32	0.10	0.05	0.04	0.05	0.02	0.03
Estradiol (pg/mL)	0.07	0.04	0.12	0.17	0.13	0.18	0.76	1.03	0.47	0.22	0.15	0.17	0.10	0.07	0.13
Free estradiol (fg/mL)	3.75	1.34	0.01	12.52	3.75	< 0.01	8.40	28.80	0.77	13.57	4.93	0.01	5.99	2.13	0.01

adjusted for age, race/ethnicity, smoking status, alcohol consumption and physical activity