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Effect of PGC-1α overexpression on mitochondria content and function in mice atrophied muscles. Mitochondria DNA content (mtDNA/nDNA) and ATP production rate (MAPR) were determined in the FVB/N mice TA (tibialis anterior) muscles. Data are mean + SEM. *P < 0.05 IM-RM versus control; **P < 0.01 IM-RM versus control; +P < 0.05 PGC-1α versus GFP. IM-RM, 14 days immobilization plus 5-day remobilization.
