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. 2012 Sep 13;9(9):1840–1848. doi: 10.1002/cbdv.201200019

1.

Cytotoxicity of Complexes 4a –4h in CH1, A549, and SW480 Cancer Cells

Compound IC50 [mm]a)
CH1 A549 SW480
4a 15±2 >250 298±34
4b 12±2 >250 240±17
4c 6.7 ±2.1 >500 119±8
4d 5.9 ±0.9 >500 94 ±23
4e 8.2 ±0.2 >250 199 ±41
4f 30±4 >500 >500
4g 14±2 >250 359±40
4h 12±1 >500 320±47

a) 50%Inhibitory concentrations in the MTT assay(96-h exposure). Values are means±standard deviations obtained from at least three independent experiments.