1.
Compound | IC50 [mm]a) | ||
---|---|---|---|
CH1 | A549 | SW480 | |
4a | 15±2 | >250 | 298±34 |
4b | 12±2 | >250 | 240±17 |
4c | 6.7 ±2.1 | >500 | 119±8 |
4d | 5.9 ±0.9 | >500 | 94 ±23 |
4e | 8.2 ±0.2 | >250 | 199 ±41 |
4f | 30±4 | >500 | >500 |
4g | 14±2 | >250 | 359±40 |
4h | 12±1 | >500 | 320±47 |
a) 50%Inhibitory concentrations in the MTT assay(96-h exposure). Values are means±standard deviations obtained from at least three independent experiments.