Table 3.
Acquired phenicol resistance genes*.
| Mechanism | Group | Gene | Gene(s) included | Length (nt) | Accession number | Coding region | Genera |
|---|---|---|---|---|---|---|---|
| Efflux | Type E-1 | cmlA1 | cmlA, cmlA2, cmlA4, cmlA5, cmlA6, cmlA7, cmlA8, cmlA10, cmlB | 1260 | M64556 | 601… 1860 | Acinetobacter, Aeromonas, Arcanobacterium, Enterobacter, Escherichia, Klebsiella, Laribacter, Pseudomonas, Salmonella, Serratia, Staphylococcus |
| Type E-2 | cml | − | 903 | M22614 | 427… 1335 | Escherichia | |
| Type E-3 | floR | cmlA-like, flo, pp-flo, cmlA9 | 1215 | AF071555 | 4445… 5659 | Acinetobacter, Aeromonas, Bordetella, Escherichia, Pasteurella, Salmonella, Stenotrophomonas, Vibrio | |
| Type E-4 | fexA | − | 1428 | AJ549214 | 177… 1604 | Bacillus, Staphylococcus | |
| Type E-5 | cml | − | 1179 | X59968 | 508… 1686 | Streptomyces | |
| Type E-6 | cmlv | − | 1311 | U09991 | 28… 1338 | Streptomyces | |
| Type E-7 | cmrA | cmr | 1176 | Z12001 | 993… 2168 | Rhodococcus | |
| Type E-8 | cmr | cmx | 1176 | U85507 | 3518… 4693 | Corynebacterium | |
| − | cmlB1 | − | 1266 | AM296481 | 776… 2041 | Bordetella | |
| − | fexB | − | 1410 | JN192453 | 10637… 12046 | Enterococcus | |
| − | pexA | − | 1248 | HM537013 | 24055… 25302 | Uncultured | |
| Inactivating enzyme | Type A-1 | catA1 | cat, catI, pp-cat | 660 | V00622 | 244… 903 | Acinetobacter, Corynebacterium, Escherichia, Klebsiella, Salmonella, Shigella |
| Type A-2 | catA2 | cat, catII | 642 | X53796 | 187… 828 | Aeromonas, Agrobacterium, Escherichia, Haemophilus, Legionella, Klebsiella, Photobacterium, Salmonella, Vibrio | |
| Type A-3 | catA3 | cat, catIII | 642 | X07848 | 272… 913 | Actinobacillus, Edwardsiella, Klebsiella, Mannheimia, Pasteurella, Shigella | |
| Type A-4 | cat | − | 654 | M11587 | 880… 1533 | Proteus | |
| Type A-5 | cat | − | 663 | P20074$ | 1002758… 1003420 | Streptomyces | |
| Type A-6 | cat86 | − | 663 | K00544 | 145… 807 | Bacillus | |
| Type A-7 | cat(pC221) | cat, catC | 648 | X02529 | 2267… 2914 | Bacillus, Enterococcus, Lactobacillus, Staphylococcus, Streptococcus | |
| Type A-8 | cat(pC223) | cat | 648 | AY355285 | 1000… 1647 | Enterococcus, Lactococcus, Listeria, Staphylococcus | |
| Type A-9 | cat(pC194) | cat, cat-TC | 651 | NC_002013 | 1260… 1910 | Bacillus, Enterococcus, Lactobacillus, Staphylococcus, Streptococcus | |
| Type A-10 | cat | − | 687 | AY238971 | 1055… 1741 | Bacillus | |
| Type A-11 | catP | catD | 624 | U15027 | 2953… 3576 | Clostridium, Neisseria | |
| Type A-12 | catS | − | 492§ | X74948 | 1… 492 | Streptococcus | |
| Type A-13 | cat | − | 624 | M35190 | 309… 932 | Campylobacter | |
| Type A-14 | cat | − | 651 | S48276 | 479… 1129 | Listonella, Photobacterium, Proteus, Vibrio | |
| Type A-15 | catB | − | 660 | M93113 | 145… 804 | Clostridium | |
| Type A-16 | catQ | − | 660 | M55620 | 459… 1118 | Clostridium | |
| Type B-1 | catB1 | cat | 630 | M58472 | 148… 777 | Agrobacterium | |
| Type B-2 | catB2 | − | 633 | AF047479 | 5957… 6589 | Acinetobacter, Aeromonas, Bordetella, Escherichia, Klebsiella, Pasteurella, Pseudomonas, Salmonella | |
| Type B-3 | catB3 | catB4, catB5, catB6, catB8 | 633 | AJ009818 | 883… 1515 | Acinetobacter, Aeromonas, Bordetella, Comamonas, Enterobacter, Escherichia, Klebsiella, Kluyvera, Morganella, Proteus, Pseudomonas, Salmonella, Serratia, Stenotrophomonas | |
| Type B-4 | catB7 | − | 639 | AF036933 | 177… 815 | Pseudomonas | |
| Type B-5 | catB9 | − | 630 | AF462019 | 27… 656 | Vibrio | |
| Type B-6 | catB10 | − | 633 | AJ878850 | 1197… 1829 | Pseudomonas | |
| rRNA methylase | − | cfr$ | − | 1050 | AJ579365 | 6290… 7339 | Bacillus, Enterococcus, Escherichia, Jeotgalicoccus, Macrococcus, Proteus, Staphylococcus |