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. 2012 Nov 16;2:162. doi: 10.3389/fonc.2012.00162

FIGURE 1.

FIGURE 1

Regulation of the polyamines putrescine, spermidine and spermine by biosynthetic enzymes (shown in green) and catabolic enzymes (shown in red). Compounds and classes of compounds that target various aspects of polyamine regulation are shown in yellow. ODC1, ornithine decarboxylase; OAZ, antizyme; AZIN, antizyme inhibitor; SRM, spermidine synthase; SMS, spermine synthase; AMD1, adenosylmethionine decarboxylase; SAT1, spermine/spermidine N1-acetyltransferase; PAOX, polyamine oxidase; SMOX, spermine oxidase.