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. 2012 Nov-Dec;47(6):714–723. doi: 10.4085/1062-6050-47.6.10

Table 2.

Summary of Reviewed Studies

Study Characteristic
Study
Hewett et al,3 1999
Soderman et al,25 2000
Heidt et al,39 2000
Myklebust et al,26 2003
Steffen et al,32 2008
Kiani et al,33 2010
Study design (CEBM level of evidence) Prospective cluster cohort (2b) Prospective randomized cluster cohort (2b)a Prospective randomized (1b) Prospective cross-over (2b) Prospective randomized cluster cohort (1b) Prospective cluster cohort (2b)
Sport Volleyball, soccer, and basketball Soccer Soccer Handball Soccer Soccer
Group size (athletes), n C = 15 teams (463) C = 6 teams (78) C = 258 players C = 60 teams (942) C = 51 teams (947) C = 49 teams (729)
I = 15 teams (366) I = 7 teams (62) I = 42 players First I = 58 teams (855) I = 58 teams (1073) I = 48 teams (777)
Second I = 52 teams (850)
Age, y 14–18 C mean = 20.5 ± 5.4 14–18 Overall mean = 21–22 Overall mean = 15.4 ± 0.8 C mean = 15.0 (range, 13.0–17.6)
I mean = 20.4 ± 4.6 I mean = 14.7 (range, 12.7–18.6)
Intervention provider Athletic trainers and physical therapists Physical therapistsc Athletic trainers Physical therapists Norwegian Football Association certified coaches and physical therapists Physician, physical therapist, and coaches
Intervention Type Stretching, plyometrics, and weight training Balance with balance boards Cardiovascular, plyometrics, strength, flexibility, agility, and sport-specific drills Balance with mats and wobble boards Core stability, balance, and plyometrics Core strengthening, and balance
 Length, min 60–90 10–15 75 15 15 20–25
 Frequency 3 d/wk Each day for 30 d then 3 d/wk for rest of the season 20 sessions (2 treadmill and 1 plyometric-based session per week) 3 d/wk for 5–7 wk then 1 d/wk for rest of the season 15 consecutive sessions then once a week for rest of the season 2 d/wk for about 2 months then 1 d/wk for rest of the season
 Duration 6 wk 6 mo 7 wk 5 mo 7.5 mo 9 mo
ACL injuries (mechanism), nb C = 5 (5 noncontact) C = 1 (no report) C = 8 (no report) First year (1998–1999) C = 29 (no report) C = 5 (2 noncontact) C = 5 (5 noncontact, 2 combined ACL and MM injury)
I = 2 (2 noncontact, 1 combined ACL and MCL injury) I = 4 (no report, 1 combined ACL and MCL injury) I = 1 (contact) Second year (1999–2000) I = 23 (no report) I = 4 (3 noncontact) I = 0
Third year (2000–2001) I = 17 (no report)

Abbreviations: ACL, anterior cruciate ligament; C, control; CEMB, Centre of Evidence Based Medicine; I, intervention; MCL, medial collateral ligament; MM, medial meniscus.

a

Although the study was a randomized controlled design, the follow-up rate was low (51.2%). Therefore, the level of evidence was rated as 2b.

b

No report indicates the researchers did not provide a description of the mechanism of ACL injury.

c

Physical therapists instructed the participants in the intervention, but the intervention was performed as a home program.