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. Author manuscript; available in PMC: 2013 Oct 11.
Published in final edited form as: J Med Chem. 2012 Sep 27;55(19):8350–8363. doi: 10.1021/jm300686p

Figure 4.

Figure 4

Antinociceptive dose–response curves for naive control mice and mice injected repeatedly with A90 doses of 17d (left panel) or morphine (right panel) i.c.v. twice daily for 3 days.