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Selected JAKinibs
| Agent | Targets | Indication/Phase |
|---|---|---|
| Tofacitinib | JAK3/JAK1/JAK2 | RA/Phase III Psoriasis/Phase II IBD/Phase II |
| VX-509 | JAK3 | RA/Phase II |
| R-348 | JAK3 | RA/Phase I |
| Ruxolitinib | JAK1/JAK2 | Approved – MF/PV |
| INCB-28050 | JAK1/JAK2 | RA/Phase II |
| GLPG-0634 | JAK1 | RA/Phase II |
| AC-430 | JAK2 | RA/Phase I Lymphoma/Phase I |
| Lestaurtinib | FLT3/TrkA/JAK2 | AML/Phase III Psoriasis/Phase II Pancreatic cancer/Phase II |
| CEP-33779 | JAK2 | Preclinical |
