Table 2.

Histopathologic Features of HNPCC Adenomas and Group-matched Controls ^*

	Controls (N = 32)	HNPCC (N = 16)
Grade of dysplasia
Low	22 (69%)	13 (81%)
High	10 (31%)	3 (19%)
Presence of necrosis	6 (19%)	1 (6%)
Presence of serrated architecture	4 (13%)	4 (25%)
Percent of villous component
Low (<25%)	28 (88%)	16 (100%)
Intermediate (25-50%)	3 (9%)	0 (0%)
High (>50%)	1 (3%)	0 (0%)
Intra-adenomatous mitotic figures
Low (<5/HPF)	24 (75%)	14 (87%)
Intermediate (5-10/HPF)	8 (25%)	2 (13%)
High (>10/HPF)	0 (0%)	0 (0%)
Adenoma-infiltrating lymphocytes
Low (<5/HPF)	28 (88%)	4 (25%)
Intermediate (5-10/HPF)	2 (6%)	5 (31%)
High (>10/HPF)	2 (6%)	7 (44%)
Intra-adenomatous apoptotic bodies
Low (<5/HPF)	5 (16%)	9 (56%)
Intermediate (5-10/HPF)	13 (41%)	5 (31%)
High (>10/HPF)	14 (43%)	2 (13%)

^*Values are given as number (percentage).

HPF: high power field (400x)